FCN1 Rabbit Polyclonal Antibody (CAB6587)
- SKU:
- CAB6587
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | FCN1 Rabbit Polyclonal Antibody |
SKU: | CAB6587 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-326 of human FCN1 (NP_001994.2). |
Sequence: | ADTC PEVK VVGL EGSD KLTI LRGC PGLP GAPG PKGE AGVI GERG ERGL PGAP GKAG PVGP KGDR GEKG MRGE KGDA GQSQ SCAT GPRN CKDL LDRG YFLS GWHT IYLP DCRP LTVL CDMD TDGG GWTV FQRR MDGS VDFY RDWA AYKQ GFGS QLGE FWLG NDNI HALT AQGS SELR VDLV DFEG NHQF AKYK SFKV ADEA EKYK LVLG AFVG GSAG NSLT GHNN NFFS TKDQ DNDV SSSN CAEK FQGA WWYA DCHA SNLN GLYL MGPH ESYA NGIN WSAA KGYK YSYK VSEM KVRP A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FCNM; FCN1 |
Positive Sample: | U-937,U-251MG,HepG2,Mouse liver,Mouse heart,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Extracellular side, Peripheral membrane protein, Secreted. |
Calculated MW: | 35kDa |
Observed MW: | 38kDa |
The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity.
Purification Method: | Affinity purification |
Gene ID: | 2219 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |