FHL3 Rabbit Polyclonal Antibody (CAB8679)
- SKU:
- CAB8679
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | FHL3 Rabbit Polyclonal Antibody |
SKU: | CAB8679 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human FHL3 (NP_004459.2). |
Sequence: | MSES FDCA KCNE SLYG RKYI QTDS GPYC VPCY DNTF ANTC AECQ QLIG HDSR ELFY EDRH FHEG CFRC CRCQ RSLA DEPF TCQD SELL CNDC YCSA FSSQ CSAC GETV MPGS RKLE YGGQ TWHE HCFL CSGC EQPL GSRS FVPD KGAH YCVP CYEN KFAP RCAR CSKT LTQG GVTY RDQP WHRE CLVC TGCQ TPLA GQQF TSRD EDPY CVAC FGEL FAPK CSSC KRPI VGLG GGKY VSFE DRHW HHNC FSCA RCST SLVG QGFV PDGD QVLC QGCS QAGP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | SLIM2; FHL3 |
Positive Sample: | LO2,HT-1080,HL-60,Mouse skeletal muscle |
Conjugate: | Unconjugated |
Cellular Localization: | nucleus, Z disc |
Calculated MW: | 31kDa |
Observed MW: | 31-36kDa |
The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2275 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |