The FHL1 Rabbit Monoclonal Antibody (CAB5018) is specifically designed for research involving FHL1, a protein associated with muscle development and function. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot and immunohistochemistry applications.FHL1, also known as four and a half LIM domains 1, is a crucial regulator of muscle cell differentiation and maintenance. Mutations in the FHL1 gene have been linked to various muscle disorders, making it a key target for research in muscle biology and disease pathology.
This antibody binds specifically to the FHL1 protein, allowing for accurate detection and analysis in various cell types and tissues.Understanding the function and regulation of FHL1 is essential for unraveling the complexities of muscle development and disease. By studying FHL1 expression and activity, researchers can gain valuable insights into the pathogenesis of muscle disorders and potentially identify new therapeutic targets for the treatment of muscle-related conditions.
Product Name:
FHL1 Rabbit Monoclonal Antibody
SKU:
CAB5018
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FHL1 (Q13642).
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
2273
Clone Number:
ARC1238
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using FHL1 Rabbit mAb (CAB5018) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
