The FH Polyclonal Antibody is a valuable tool for research involving FH (factor H), a key regulator of the complement system. The antibody, produced by Assay Genie, is raised in rabbits and specifically designed for use in Western blot applications. It is highly reactive with human samples, enabling accurate detection and analysis of FH protein levels in various cell types.FH is a critical component of the complement system, playing a crucial role in regulating the immune response and protecting the body against infections. Dysregulation of FH has been implicated in various diseases, including age-related macular degeneration and atypical hemolytic uremic syndrome.
Research into FH can provide insights into the pathogenesis of these diseases and potentially lead to the development of targeted therapies.By utilizing the FH Polyclonal Antibody in your research, you can explore the functions and mechanisms of FH in different biological contexts. Its high specificity and sensitivity make it an excellent tool for investigating the role of FH in immunology, inflammation, and autoimmunity. Unlock the potential of FH research with the FH Polyclonal Antibody from Assay Genie.
Product Name:
FH Polyclonal Antibody
SKU:
CAB21403
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FH (NP_000134.2).
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Purification Method:
Affinity purification
Gene ID:
2271
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FH Rabbit pAb (CAB21403) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
