FH Polyclonal Antibody (CAB21403)
- SKU:
- CAB21403
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | FH Polyclonal Antibody |
SKU: | CAB21403 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human FH (NP_000134.2). |
Sequence: | FRIE YDTF GELK VPND KYYG AQTV RSTM NFKI GGVT ERMP TPVI KAFG ILKR AAAE VNQD YGLD PKIA NAIM KAAD EVAE GKLN DHFP LVVW QTGS GTQT N |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MCL; FMRD; HsFH; LRCC; HLRCC; MCUL1; FH |
Positive Sample: | 293T,Hela,NIH/3T3,C2C12,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion. |
Calculated MW: | 55kDa |
Observed MW: | 49kDa |
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Purification Method: | Affinity purification |
Gene ID: | 2271 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |