FH Rabbit Polyclonal Antibody (CAB5688)
- SKU:
- CAB5688
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | FH Rabbit Polyclonal Antibody |
SKU: | CAB5688 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-510 of human FH (NP_000134.2). |
Sequence: | ASQN SFRI EYDT FGEL KVPN DKYY GAQT VRST MNFK IGGV TERM PTPV IKAF GILK RAAA EVNQ DYGL DPKI ANAI MKAA DEVA EGKL NDHF PLVV WQTG SGTQ TNMN VNEV ISNR AIEM LGGE LGSK IPVH PNDH VNKS QSSN DTFP TAMH IAAA IEVH EVLL PGLQ KLHD ALDA KSKE FAQI IKIG RTHT QDAV PLTL GQEF SGYV QQVK YAMT RIKA AMPR IYEL AAGG TAVG TGLN TRIG FAEK VAAK VAAL TGLP FVTA PNKF EALA AHDA LVEL SGAM NTTA CSLM KIAN DIRF LGSG PRSG LGEL ILPE NEPG SSIM PGKV NPTQ CEAM TMVA AQVM GNHV AVTV GGSN GHFE LNVF KPMM IKNV LHSA RLLG DASV SFTE NCVV GIQA NTER INKL MNES LMLV TALN PHIG YDKA AKIA KTAH KNGS TLKE TAIE LGYL TAEQ FDEW VKPK DMLG PK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | MCL; FMRD; HsFH; LRCC; HLRCC; MCUL1; FH |
Positive Sample: | HeLa,NIH/3T3,C2C12,C6,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion. |
Calculated MW: | 55kDa |
Observed MW: | 47kDa |
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
Purification Method: | Affinity purification |
Gene ID: | 2271 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |