The FGL2 Polyclonal Antibody (CAB13755) is a valuable tool for researchers studying FGL2, a protein involved in immune regulation and coagulation. This antibody, developed through rabbit immunization, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the FGL2 protein, this antibody enables the detection and analysis of FGL2 in a variety of cell types, making it an ideal choice for studies in immunology and hemostasis research.
FGL2, also known as fibrinogen-like protein 2, plays a crucial role in regulating immune responses and promoting blood coagulation. Understanding the function of FGL2 is essential for investigating its involvement in diseases such as autoimmune disorders, inflammatory conditions, and thrombotic disorders. By targeting FGL2 with this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic strategies.
Product Name:
FGL2 Rabbit Polyclonal Antibody
SKU:
CAB13755
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-140 of human FGL2 (NP_006673.1).
Sequence:
NNET EEIK DERA KDVC PVRL ESRG KCEE AGEC PYQV SLPP LTIQ LPKQ FSRI EEVF KEVQ NLKE IVNS LKKS CQDC KLQA DDNG DPGR NGLL LPST GAPG EVGD NRVR ELES EVNK L
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
FGL2; T49; pT49
Positive Sample:
HepG2
Conjugate:
Unconjugated
Cellular Localization:
Secreted.
Calculated MW:
50kDa
Observed MW:
70kDa
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.
Purification Method:
Affinity purification
Gene ID:
10875
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using FGL2 Rabbit pAb (CAB13755) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
