FGG Rabbit Polyclonal Antibody (CAB5642)
- SKU:
- CAB5642
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | FGG Rabbit Polyclonal Antibody |
SKU: | CAB5642 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-330 of human FGG (NP_000500.2). |
Sequence: | GIAD FLST YQTK VDKD LQSL EDIL HQVE NKTS EVKQ LIKA IQLT YNPD ESSK PNMI DAAT LKSR KMLE EIMK YEAS ILTH DSSI RYLQ EIYN SNNQ KIVN LKEK VAQL EAQC QEPC KDTV QIHD ITGK DCQD IANK GAKQ SGLY FIKP LKAN QQFL VYCE IDGS GNGW TVFQ KRLD GSVD FKKN WIQY KEGF GHLS PTGT TEFW LGNE KIHL ISTQ SAIP YALR VELE DWNG RTST ADYA MFKV GPEA DKYR LTYA YFAG GDAG DAFD GFDF GDDP SDKF F |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FGG |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 2266 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |