FGFR4 Rabbit Monoclonal Antibody (CAB9197)
- SKU:
- CAB9197
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FGFR4 Rabbit Monoclonal Antibody |
SKU: | CAB9197 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-802 of human FGFR4 (P22455). |
Sequence: | SLLR EGHR MDRP PHCP PELY GLMR ECWH AAPS QRPT FKQL VEAL DKVL LAVS EEYL DLRL TFGP YSPS GGDA SSTC SSSD SVFS HDPL PLGS SSFP FGSG VQT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TKF; JTK2; CD334; FGFR4 |
Positive Sample: | HepG2,MCF7,Raji,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endoplasmic reticulum, Endosome, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 88kDa |
Observed MW: | 95kDa/125kDa |
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
Purification Method: | Affinity purification |
Gene ID: | 2264 |
Clone Number: | ARC1474 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |