FGFR1OP2 Antibody (PACO26761)
- SKU:
- PACO26761
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
FGFR1OP2 Antibody (PACO26761)
The FGFR1OP2 Antibody (PACO26761) is a high-quality antibody designed for research involving FGFR1OP2, a protein associated with fibroblast growth factor receptor (FGFR) signaling pathways. The antibody, developed and validated specifically for use in Western blot applications, is raised in rabbits and has been shown to exhibit high reactivity with human samples.FGFR1OP2, also known as fibroblast growth factor receptor substrate 2 (FRS2), is a key player in the regulation of FGFR signaling, which is crucial for cell growth, differentiation, and survival. By detecting and binding to FGFR1OP2, this antibody enables researchers to investigate the role of FGFR1OP2 in various cell types and physiological processes, particularly in the context of cancer and other diseases where aberrant FGFR signaling is implicated.
With its reliability and specificity in detecting FGFR1OP2, this antibody is an essential tool for researchers studying cell signaling pathways, cancer biology, and potential therapeutic targets. Its versatility and accuracy make it a valuable asset for advancing our understanding of FGFR signaling and its role in disease development and progression.
| Antibody Name: | FGFR1OP2 Antibody (PACO26761) |
| Antibody SKU: | PACO26761 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human FGFR1 oncogene partner 2 protein (1-172AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: FGFR1OP2 antibody at 6µg/ml Lane 1: Mouse gonadal tissue Lane 2: Human placenta tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30, 25, 21 kDa Observed band size: 30 kDa . |
| Background: | May be involved in wound healing pathway. |
| Synonyms: | FGFR1 oncogene partner 2, FGFR1OP2 |
| UniProt Protein Function: | FGFR1OP2: May be involved in wound healing pathway. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity. Belongs to the SIKE family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 12p11.23Cellular Component: cytosolMolecular Function: protein binding; protein-tyrosine kinase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NVK5 |
| NCBI GenInfo Identifier: | 74734519 |
| NCBI Gene ID: | 26127 |
| NCBI Accession: | Q9NVK5.1 |
| UniProt Secondary Accession: | Q9NVK5,Q6R955, Q8N5L7, Q9P034, Q9UFK8 |
| UniProt Related Accession: | Q9NVK5 |
| Molecular Weight: | 20,175 Da |
| NCBI Full Name: | FGFR1 oncogene partner 2 |
| NCBI Synonym Full Names: | FGFR1 oncogene partner 2 |
| NCBI Official Symbol: | FGFR1OP2Â Â |
| NCBI Official Synonym Symbols: | WIT3.0; HSPC123-like  |
| NCBI Protein Information: | FGFR1 oncogene partner 2 |
| UniProt Protein Name: | FGFR1 oncogene partner 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | FGFR1 oncogene partner |
| UniProt Gene Name: | FGFR1OP2Â Â |
| UniProt Entry Name: | FGOP2_HUMAN |
| Antibodies |
| FGFR1OP2 Antibody (PACO09288) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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