FGFR1OP Rabbit Polyclonal Antibody (CAB17627)
- SKU:
- CAB17627
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FGFR1OP Rabbit Polyclonal Antibody |
SKU: | CAB17627 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human FGFR1OP (NP_919410.1). |
Sequence: | MAAT AAAV VAEE DTEL RDLL VQTL ENSG VLNR IKAE LRAA VFLA LEEQ EKVE NKTP LVNE SLKK FLNT KD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FOP; FGFR1OP |
Positive Sample: | Mouse kidney,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
Purification Method: | Affinity purification |
Gene ID: | 11116 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |