The FGFBP1 Polyclonal Antibody (CAB7458) is a valuable tool for researchers studying FGFBP1, a protein involved in the regulation of fibroblast growth factors. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the FGFBP1 protein, this antibody allows for the detection and analysis of FGFBP1 in a variety of cell types, making it an ideal choice for studies in the fields of cell biology and cancer research.FGFBP1 is known to play a crucial role in the regulation of fibroblast growth factors, which are important in a variety of cellular processes including cell proliferation and differentiation.
Dysregulation of FGFBP1 has been implicated in various diseases such as cancer, making it a promising target for therapeutic interventions. By using the FGFBP1 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms of FGFBP1 function and potentially identify new strategies for treating diseases related to its dysregulation.
Product Name:
FGFBP1 Rabbit Polyclonal Antibody
SKU:
CAB7458
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-234 of human FGFBP1 (NP_005121.1).
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
Purification Method:
Affinity purification
Gene ID:
9982
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FGFBP1 antibody (CAB7458) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
