The FGF4 Polyclonal Antibody (CAB14731) is a valuable tool for researchers studying the Fibroblast Growth Factor 4 (FGF4) protein, a critical player in cellular growth and development. This antibody, generated in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications.FGF4 is a key signaling molecule involved in cell proliferation, differentiation, and migration, making it indispensable for various processes such as embryonic development, tissue repair, and angiogenesis. By targeting the FGF4 protein, researchers can gain insights into its role in cancer progression, stem cell maintenance, and tissue regeneration.
The FGF4 Polyclonal Antibody enables the detection and analysis of FGF4 expression in different cell types, providing a versatile tool for investigations in developmental biology, cancer research, and regenerative medicine. By understanding the functions of FGF4 at the molecular level, researchers can uncover new therapeutic targets and strategies for treating diseases associated with aberrant FGF4 signaling pathways.
Product Name:
FGF4 Rabbit Polyclonal Antibody
SKU:
CAB14731
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-206 of human FGF4 (NP_001998.1).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.
Purification Method:
Affinity purification
Gene ID:
2249
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat liver, using FGF4 Rabbit pAb (CAB14731) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
