The FGF3 Polyclonal Antibody (CAB16850) is a powerful tool for researchers studying fibroblast growth factor 3 (FGF3), a key player in cell growth and development. This antibody, raised in rabbits, shows high reactivity with FGF3 in human samples, making it ideal for use in Western blot applications.FGF3 is a growth factor that plays crucial roles in various biological processes, including embryonic development, tissue repair, and angiogenesis. Dysregulation of FGF3 has been implicated in a range of diseases, such as cancer, cardiovascular disorders, and developmental abnormalities.
Therefore, studying the expression and function of FGF3 is essential for understanding these pathological conditions and developing targeted therapies.By specifically binding to FGF3, this antibody enables precise detection and analysis of the protein in different cell types, offering valuable insights into its role in normal physiology and disease. Researchers in the fields of molecular biology, cell biology, and cancer research will find this antibody indispensable for their studies on FGF3 and its implications in various biological processes.
Product Name:
FGF3 Rabbit Polyclonal Antibody
SKU:
CAB16850
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGF3 (NP_005238.1).
cytoplasm, extracellular region, extracellular space
Calculated MW:
27kDa
Observed MW:
27kDa
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
Purification Method:
Affinity purification
Gene ID:
2248
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat liver, using FGF3 Rabbit pAb (CAB16850) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.