Fgf23 Antibody (PACO26753)
- SKU:
- PACO26753
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Fgf23 Antibody (PACO26753)
The FGF23 Antibody (PAC026753) is a valuable tool for researchers studying fibroblast growth factor 23 (FGF23), a key regulator of phosphate and vitamin D metabolism. This polyclonal antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By targeting the FGF23 protein, this antibody enables precise detection and analysis in various cell types, providing crucial insights into the role of FGF23 in physiological processes and diseases.
FGF23 is known for its essential role in maintaining mineral homeostasis, particularly in regulating phosphate levels in the body. Dysregulation of FGF23 has been linked to various disorders, including chronic kidney disease, hypophosphatemic rickets, and tumor-induced osteomalacia. Studying the function and expression of FGF23 with the PAC026753 antibody is instrumental in unraveling the mechanisms underlying these conditions and developing targeted therapies to address them.
| Antibody Name: | Fgf23 Antibody (PACO26753) |
| Antibody SKU: | PACO26753 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Fibroblast growth factor 23 protein (25-251AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Fgf23 antibody at 2µg/ml + Rat heart tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa . |
| Background: | Regulator of phosphate homeostasis.Inhibits renal tubular phosphate transport by reducing SLC34A1 levels.Regulator of vitamin-D metabolism .Negatively regulates osteoblasts differentiation and .matrix mineralization.Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 .expression in the presence of KL. |
| Synonyms: | Fibroblast growth factor 23 (FGF-23), Fgf23 |
| UniProt Protein Function: | Function: Regulator of phosphate homeostasis Inhibits renal tubular phosphate transport by reducing SLC34A1 levels Regulator of vitamin-D metabolism Negatively regulates osteoblasts differentiation and matrix mineralization Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL.2 PublicationsManual assertion based on experiment in:Ref.2 |
| UniProt Code: | Q8VI82 |
| NCBI GenInfo Identifier: | 18543369 |
| NCBI Gene ID: | 170583 |
| NCBI Accession: | NP_570110.1 |
| UniProt Related Accession: | Q8VI82 |
| Molecular Weight: | 27,912 Da |
| NCBI Full Name: | fibroblast growth factor 23 |
| NCBI Synonym Full Names: | fibroblast growth factor 23 |
| NCBI Official Symbol: | Fgf23Â Â |
| NCBI Protein Information: | fibroblast growth factor 23; FGF-23 |
| UniProt Protein Name: | Fibroblast growth factor 23 |
| Protein Family: | Fibroblast growth factor |
| UniProt Gene Name: | Fgf23Â Â |
| UniProt Entry Name: | FGF23_RAT |
| ELISA Kits |
| Rat FGF 23 / Fibroblast Growth Factor 23 ELISA Kit |
| Rat Fibroblast growth factor 23 (Fgf23) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
FGF23 Rabbit Polyclonal Antibody (CAB6124)
FGF23 Rabbit Polyclonal Antibody (CAB14073)
Mouse Fibroblast growth factor 23 (Fgf23) ELISA Kit (MOEB0569)
Mouse FGF23 (Fibroblast Growth Factor 23) ELISA Kit (MOES01695)
