The FGF22 Polyclonal Antibody (PAC019658) is a powerful tool for researchers studying fibroblast growth factor 22 (FGF22), a protein involved in neuronal development and function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting FGF22 in human samples, making it ideal for use in Western blotting experiments.FGF22 is known to play a crucial role in neurogenesis, neuronal differentiation, and synaptic plasticity, making it a key player in the development and maintenance of the nervous system.
Research on FGF22 has implications for understanding various neurological disorders, such as Alzheimer's disease, Parkinson's disease, and depression.By using the FGF22 Polyclonal Antibody, researchers can gain insights into the expression levels and localization of FGF22 in different cell types and tissues, paving the way for advancements in neuroscience and the development of potential therapeutic interventions targeting FGF22-related pathways.
Antibody Name:
FGF22 Antibody (PACO19658)
Antibody SKU:
PACO19658
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human FGF22
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19658(FGF22 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19658(FGF22 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Synonyms:
fibroblast growth factor 22
UniProt Protein Function:
FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
