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FGF22 Antibody (PACO00801)

SKU:
PACO00801
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
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Description

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FGF22 Antibody (PACO00801)

The FGF22 Polyclonal Antibody (PACO00801) is a valuable tool for researchers studying FGF22, a member of the fibroblast growth factor (FGF) family known for its role in neuronal development and regeneration. Raised in rabbits, this antibody is highly specific and reacts strongly with human samples, making it an ideal choice for Western blot applications.FGF22 is important for promoting neuronal survival, axon growth, and synaptic plasticity in the central nervous system. It has been implicated in various neurological disorders, making it a promising target for research in neurobiology and neurodegenerative diseases.

The FGF22 Polyclonal Antibody binds specifically to the FGF22 protein, allowing for accurate detection and analysis in a variety of cell types.Researchers interested in understanding the functions of FGF22 in neuronal development, regeneration, and disease pathogenesis will benefit from using this antibody in their studies. By elucidating the mechanisms by which FGF22 influences neural processes, insights gained from this research may lead to the development of novel therapeutic strategies for neurological disorders.

Antibody Name:FGF22 Antibody
Antibody SKU:PACO00801
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human FGF-22.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:FGF22; Fibroblast growth factor 22; FGF-22
UniProt Protein Function:FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi apparatus; extracellular space; cell surface; extracellular region; nucleolus

Molecular Function:growth factor activity; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation

NCBI Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Code:Q9HCT0
NCBI GenInfo Identifier:13626689
NCBI Gene ID:27006
NCBI Accession:Q9HCT0.1
UniProt Secondary Accession:Q9HCT0,B2RPH4,
UniProt Related Accession:Q9HCT0
Molecular Weight:19,663 Da
NCBI Full Name:Fibroblast growth factor 22
NCBI Synonym Full Names:fibroblast growth factor 22
NCBI Official Symbol:FGF22  
NCBI Protein Information:fibroblast growth factor 22; FGF-22
UniProt Protein Name:Fibroblast growth factor 22
Protein Family:Fibroblast growth factor
UniProt Gene Name:FGF22  
UniProt Entry Name:FGF22_HUMAN

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