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Fgf21 Antibody (PACO26749)

SKU:
PACO26749
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
Frequently bought together:

Description

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Fgf21 Antibody (PACO26749)

The FGF21 Polyclonal Antibody (PACO26749) is a vital tool for researchers investigating the role of Fibroblast Growth Factor 21 (FGF21) in metabolic regulation and energy homeostasis. This antibody, produced in rabbits, demonstrates high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By targeting the FGF21 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component in studies focused on metabolic disorders, obesity, and diabetes.

FGF21 is a key player in metabolic processes, regulating glucose and lipid metabolism, as well as energy expenditure. Its involvement in these pathways has positioned it as a promising target for therapeutic interventions aimed at combating metabolic diseases and promoting overall health. The FGF21 Polyclonal Antibody provides researchers with a reliable tool to further explore the mechanisms underlying FGF21 activity, ultimately leading to advancements in the development of novel treatments for metabolic disorders.

Antibody Name:Fgf21 Antibody (PACO26749)
Antibody SKU:PACO26749
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse Fibroblast growth factor 21 protein (29-210AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB.
Synonyms:Fibroblast growth factor 21 (FGF-21), Fgf21
UniProt Protein Function:FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Cellular Component: extracellular region; extracellular space

Molecular Function:fibroblast growth factor receptor binding; growth factor activity; receptor binding

Biological Process: fibroblast growth factor receptor signaling pathway; positive regulation of cell proliferation; positive regulation of glucose import

UniProt Code:Q9JJN1
NCBI GenInfo Identifier:13626695
NCBI Gene ID:105242481
NCBI Accession:Q9JJN1.1
Molecular Weight:23,237 Da
NCBI Full Name:Fibroblast growth factor 21
NCBI Official Symbol:LOC105242481  
NCBI Protein Information:fibroblast growth factor 21
UniProt Protein Name:Fibroblast growth factor 21
Protein Family:Fibroblast growth factor
UniProt Gene Name:Fgf21  
UniProt Entry Name:FGF21_MOUSE

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