The FGF21 Polyclonal Antibody (CAB10368) is a valuable tool for researchers studying the fibroblast growth factor 21 (FGF21) protein, known for its role in metabolic regulation and energy homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the FGF21 protein, researchers can accurately detect and quantify its presence in various cell types, aiding in the investigation of FGF21's functions in metabolism, obesity, and related metabolic disorders.
FGF21 is a key metabolic regulator involved in glucose and lipid metabolism, as well as in controlling energy expenditure. Dysregulation of FGF21 signaling has been linked to metabolic diseases such as type 2 diabetes and obesity, highlighting the importance of studying FGF21's mechanisms and potential therapeutic applications. By utilizing the FGF21 Polyclonal Antibody, researchers can deepen their understanding of FGF21's physiological roles and potentially discover new targets for metabolic therapies.
Product Name:
FGF21 Rabbit Polyclonal Antibody
SKU:
CAB10368
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 29-209 of human FGF21 (NP_061986.1).
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue.
Purification Method:
Affinity purification
Gene ID:
26291
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FGF21 antibody (CAB10368) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
