FGF2 Rabbit Polyclonal Antibody (CAB17989)
- SKU:
- CAB17989
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | FGF2 Rabbit Polyclonal Antibody |
SKU: | CAB17989 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 143-288 of FGF2 (NP_001997.5). |
Sequence: | PALP EDGG SGAF PPGH FKDP KRLY CKNG GFFL RIHP DGRV DGVR EKSD PHIK LQLQ AEER GVVS IKGV CANR YLAM KEDG RLLA SKCV TDEC FFFE RLES NNYN TYRS RKYT SWYV ALKR TGQY KLGS KTGP GQKA ILFL PMSA KS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | BFGF; FGFB; FGF-2; HBGF-2; FGF2 |
Positive Sample: | Mouse lung |
Cellular Localization: | Nucleus, Secreted. |
Calculated MW: | 31kDa |
Observed MW: | 18kDa,22kDa,24kDa/24kDa |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method: | Affinity purification |
Gene ID: | 2247 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |