The FGF2 Polyclonal Antibody is a specialized tool for studying Fibroblast Growth Factor 2 (FGF2), a key signaling molecule involved in cell growth, development, and wound healing. This antibody, produced in rabbits, is specifically designed for use in various research applications, including Western blotting and immunohistochemistry.FGF2 is known for its roles in promoting cell proliferation, angiogenesis, and tissue repair. By targeting FGF2, researchers can investigate its functions in different biological processes and diseases, such as cancer, cardiovascular disorders, and neurodegenerative conditions.
The FGF2 Polyclonal Antibody provides reliable detection and analysis of FGF2 protein levels in experimental samples, facilitating in-depth studies in cell biology and pathology.With its high specificity and sensitivity, this antibody is a valuable tool for scientists looking to unravel the complex functions of FGF2 in diverse physiological and pathological contexts. Its application extends to various fields, including regenerative medicine, oncology, and cardiovascular research, where understanding FGF2 signaling pathways is crucial for developing targeted therapies and diagnostic tools.
Product Name:
FGF2 Polyclonal Antibody
SKU:
CAB21402
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method:
Affinity purification
Gene ID:
2247
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse ovary, using FGF2 Rabbit pAb (CAB21402) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
