The FGF2 Polyclonal Antibody (CAB0235) is a valuable tool for researchers studying FGF2, a potent growth factor involved in various cellular processes, including cell proliferation, differentiation, and migration. This antibody, produced using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.FGF2, also known as basic fibroblast growth factor, plays a crucial role in tissue repair and regeneration, making it a target of interest in studies related to wound healing, development, and cancer biology.
By targeting the FGF2 protein, researchers can investigate its functions in different cell types and pathways, providing insights into its therapeutic potential in various disease contexts.The FGF2 Polyclonal Antibody is an essential tool for researchers seeking to understand the intricate mechanisms underlying FGF2 signaling and its impact on cellular physiology. Its specificity and reliability make it an ideal choice for immunology and cancer research, offering valuable insights into the role of FGF2 in health and disease.
Product Name:
FGF2 Rabbit Polyclonal Antibody
SKU:
CAB0235
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 143-288 of human FGF2 (NP_001997.5).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method:
Affinity purification
Gene ID:
2247
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using FGF2 Rabbit pAb (CAB0235) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
