FGF2 Polyclonal Antibody (CAB21402)
- SKU:
- CAB21402
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | FGF2 Polyclonal Antibody |
| SKU: | CAB21402 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5). |
| Sequence: | RAPE RVGG RGRG RGTA APRA APAA RGSR PGPA GTMA AGSI TTLP ALPE DGGS GAFP PGHF KDPK RLYC KNGG FFLR IHPD GRVD GVRE KSDP HIKL QLQA E |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:1000 - 1:5000 |
| Synonyms: | BFGF; FGFB; FGF-2; HBGF-2; F2 |
| Positive Sample: | Mouse ovary |
| Conjugate: | Unconjugated |
| Cellular Localization: | Nucleus, Secreted. |
| Calculated MW: | 31kDa |
| Observed MW: | 18kDa/22kDa/24kDa |
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
| Purification Method: | Affinity purification |
| Gene ID: | 2247 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of lysates from Mouse ovary, using FGF2 Rabbit pAb (CAB21402) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s. |
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