The FGF2 Monoclonal Antibody (CAB22330) is a highly specific tool for studying Fibroblast Growth Factor 2 (FGF2), a key player in cell growth, development, and wound healing. This antibody, produced using advanced monoclonal technology, is validated for use in various applications, including immunohistochemistry, immunoprecipitation, and flow cytometry.FGF2 is a potent growth factor that plays a crucial role in angiogenesis, tissue repair, and embryonic development. Dysregulation of FGF2 signaling is associated with various diseases, including cancer, cardiovascular disorders, and neurological conditions. The FGF2 Monoclonal Antibody allows researchers to investigate the expression and function of FGF2 in different cell types and tissues, providing insights into its role in disease pathogenesis and potential therapeutic interventions.
Whether studying basic biological mechanisms or exploring novel treatment strategies, the FGF2 Monoclonal Antibody is a valuable tool for researchers in the fields of molecular biology, cell biology, and biomedicine. Its high specificity and sensitivity ensure reliable and reproducible results, contributing to advancements in our understanding of FGF2-mediated processes and their implications for human health.
Product Name:
FGF2 Monoclonal Antibody
SKU:
CAB22330
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FGF2 (NP_001997.5).
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Purification Method:
Affinity purification
Gene ID:
2247
Clone Number:
ARC51110
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of SKOV3, using FGF2 antibody (CAB22330) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
