The FGF2 Polyclonal Antibody (PACO64019) is a valuable tool for researchers studying Fibroblast Growth Factor 2 (FGF2), a key player in cell proliferation, migration, and differentiation. This antibody, generated in rabbits, is highly specific to human FGF2 and has been validated for use in Western blot applications.FGF2, also known as basic fibroblast growth factor, is essential for various biological processes, including embryonic development, tissue repair, and angiogenesis. Dysregulation of FGF2 signaling has been implicated in a variety of diseases, including cancer, cardiovascular disorders, and neurological conditions.
By targeting FGF2 with this antibody, researchers can gain insight into its role in disease pathogenesis and potential therapeutic interventions.With its high reactivity and specificity, the FGF2 Polyclonal Antibody is an essential tool for investigating the function and regulation of FGF2 in different cellular contexts. Whether studying cancer biology, developmental processes, or regenerative medicine, this antibody enables precise detection and analysis of FGF2, advancing our understanding of its impact on human health.
Antibody Name:
Fgf2 Antibody (PACO64019)
Antibody SKU:
PACO64019
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:2000
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Fibroblast growth factor 2 protein (10-154AA)
Western Blot. Positive WB detected in: Rat Heart tissue, Rat Brain tissue. All lanes: Fgf2 antibody at 1:1000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 18 kDa. Observed band size: 18 kDa.
FGF2: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2. Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. Belongs to the heparin-binding growth factors family. 4 isoforms of the human protein are produced by alternative initiation.
UniProt Protein Details:
Protein type:Activator; Motility/polarity/chemotaxis
