The FGF16 Antibody (PAC002117) is a high-quality polyclonal antibody developed for research purposes, specifically targeting the Fibroblast Growth Factor 16 (FGF16) protein. This antibody, produced in rabbits, has been validated for use in various applications such as Western blotting, immunohistochemistry, and immunofluorescence.FGF16 is a member of the Fibroblast Growth Factor family known for its role in cell growth, development, and differentiation. It plays a crucial part in various physiological processes including tissue repair, angiogenesis, and embryonic development.
Research on FGF16 has shown its involvement in various diseases such as cancer, cardiovascular disorders, and neurological conditions.The FGF16 Antibody is designed to specifically bind to FGF16, allowing for the detection and analysis of this important protein in a wide range of cell types and tissues. Its high reactivity with human samples makes it an ideal tool for studying the function and regulation of FGF16 in biological processes, making it a valuable asset for studies in cell biology, developmental biology, and disease research.
Antibody Name:
FGF16 Antibody
Antibody SKU:
PACO02117
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human FGF-16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
FGF16; Fibroblast growth factor 16; FGF-16
UniProt Protein Function:
FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.Protein type: CytokineChromosomal Location of Human Ortholog: Xq13Cellular Component: extracellular region; extracellular spaceMolecular Function: 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activityBiological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; metabolic process; organ morphogenesis; phosphoinositide-mediated signaling; regulation of endothelial cell proliferation; regulation of MAP kinase activity; regulation of phosphoinositide 3-kinase cascade; response to temperature stimulus; signal transductionDisease: Metacarpal 4-5 Fusion
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]
