The FGF11 Polyclonal Antibody (PACO02213) is specifically designed for research involving FGF11, a member of the fibroblast growth factor (FGF) family known for its role in nervous system development and function. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in Western blot applications.FGF11, also called fibroblast growth factor 11, is involved in various biological processes including neuronal differentiation, survival, and synaptic plasticity. Dysregulation of FGF11 has been linked to neurological disorders such as epilepsy, schizophrenia, and Alzheimer's disease, making it a promising target for therapeutic intervention.
By using the FGF11 Polyclonal Antibody, researchers can effectively detect and analyze FGF11 protein expression in different cell types, providing valuable insights into its function and potential therapeutic applications in neurobiology and neurological disease research. Understanding the role of FGF11 is crucial for developing targeted therapies that may help in the treatment of various neurological disorders.
Antibody Name:
FGF11 Antibody
Antibody SKU:
PACO02213
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the Internal region of human FGF-11.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
FGF11: Probably involved in nervous system development and function. Belongs to the heparin-binding growth factors family.Protein type: Cell development/differentiationChromosomal Location of Human Ortholog: 17p13.1Biological Process: cell-cell signaling; nervous system development; signal transduction
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this gene has not yet been determined. The expression pattern of the mouse homolog implies a role in nervous system development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
