The FGD5 Polyclonal Antibody (CAB15212) is a valuable tool for researchers studying FGD5, a protein involved in cell signaling pathways related to cell proliferation and migration. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By binding to the FGD5 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component for investigations in the fields of cell biology and cancer research.FGD5, also known as Rho GDP-dissociation inhibitor 4 (RhoGDI4), is a key player in the regulation of Rho GTPases, which are critical for controlling cellular processes such as cytoskeletal organization and cell motility.
Dysregulation of FGD5 has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target. By studying the function of FGD5, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially discover new treatment strategies.
Product Name:
FGD5 Rabbit Polyclonal Antibody
SKU:
CAB15212
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human FGD5 (NP_689749.3).
Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in several processes, including filopodium assembly; regulation of GTPase activity; and regulation of cell shape. Located in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
152273
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using FGD5 Rabbit pAb (CAB15212) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
