The FGB Polyclonal Antibody (CAB1401) is a valuable tool for research involving FGB, a protein involved in blood clotting and the immune response. This antibody is produced in rabbits and has been shown to be highly reactive with human samples, making it ideal for use in various research applications.The FGB Polyclonal Antibody is specifically validated for use in Western blot applications, allowing researchers to detect and analyze the FGB protein in different cell types.
This makes it a valuable tool for studies in immunology, hematology, and other fields where the FGB protein plays a role.Overall, the FGB Polyclonal Antibody (CAB1401) is essential for researchers looking to investigate the function and significance of the FGB protein in various biological processes. Its reliability and specificity make it a valuable asset in the study of blood clotting disorders, immune responses, and other related research areas.
Product Name:
FGB Rabbit Polyclonal Antibody
SKU:
CAB1401
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-222 of human FGB (NP_005132.2).
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Fibrinogen serves key roles in hemostasis and antimicrobial host defense. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.
Purification Method:
Affinity purification
Gene ID:
2244
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FGB antibody (CAB1401) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
