The FFAR4 Polyclonal Antibody (CAB18689) is a valuable tool for research involving FFAR4, a G-protein coupled receptor involved in metabolic regulation and energy balance. This antibody, raised in rabbits, offers high reactivity with human samples and is optimized for use in Western blot applications. By binding to the FFAR4 protein, this antibody enables precise detection and analysis in various cell types, making it an excellent choice for studies in metabolism, obesity, and diabetes research.
FFAR4, also known as GPR120, is a key mediator in the control of glucose and lipid metabolism, making it a potential target for therapeutic intervention in metabolic disorders. Its role in regulating insulin sensitivity and inflammation puts it at the forefront of research into metabolic diseases and associated complications. Understanding the function of FFAR4 is essential for developing novel treatments that target this receptor and its downstream signaling pathways.
Product Name:
FFAR4 Rabbit Polyclonal Antibody
SKU:
CAB18689
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 333-377 of human FFAR4 (NP_859529.2).
Sequence:
NPIL YNMT LCRN EWKK IFCC FWFP EKGA ILTD TSVK RNDL SIIS G
HT-29,BxPC-3,RAW264.7,Mouse large intestine,Rat large intestine,Rat small intestine
Cellular Localization:
ciliary membrane, cilium, plasma membrane
Calculated MW:
40kDa
Observed MW:
42kDa
This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
338557
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FFAR4 Rabbit pAb (CAB18689) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
