The FEZ1 Polyclonal Antibody (CAB15362) is a valuable tool for researchers studying FEZ1, a protein involved in neuronal development and function. This antibody, produced in rabbits, has high specificity for human samples and is suitable for Western blotting applications. By targeting the FEZ1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for neuroscience and neurobiology research.FEZ1, also known as fasciculation and elongation protein zeta 1, plays a crucial role in neuronal morphology, axonal growth, and synaptic plasticity. Its involvement in these processes makes it a key player in neurodevelopment and neurological disorders.
Research into FEZ1's function can provide valuable insights into conditions like Alzheimer's disease, Parkinson's disease, and schizophrenia, offering potential therapeutic targets for future treatments.With its ability to specifically detect FEZ1 in human samples, the CAB15362 antibody is a trusted tool for researchers investigating the molecular mechanisms underlying neuronal development and function. By utilizing this antibody, researchers can advance our understanding of FEZ1's role in the nervous system and contribute to the development of new therapies for neurological disorders.
Product Name:
FEZ1 Rabbit Polyclonal Antibody
SKU:
CAB15362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human FEZ1 (NP_005094.1).
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
Purification Method:
Affinity purification
Gene ID:
9638
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FEZ1 Rabbit pAb (CAB15362) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
