FEZ1 Rabbit Polyclonal Antibody (CAB15361)
- SKU:
- CAB15361
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | FEZ1 Rabbit Polyclonal Antibody |
SKU: | CAB15361 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human FEZ1 (NP_005094.1). |
Sequence: | MEAP LVSL DEEF EDLR PSCS EDPE EKPQ CFYG SSPH HLED PSLS ELEN FSSE IISF KSME DLVN EFDE KLNV CFRN YNAK TENL APVK NQLQ IQEE EETL QDEE VWDA LTDN YIPS LSED WRDP NIEA LNGN CSDT EIHE KEEE EFNE KSEN DSGI NEEP |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | UNC-76; FEZ1 |
Positive Sample: | U-251MG |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 45kDa |
Observed MW: | 71kDa |
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
Purification Method: | Affinity purification |
Gene ID: | 9638 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |