FES Rabbit Polyclonal Antibody (CAB2578)
- SKU:
- CAB2578
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FES Rabbit Polyclonal Antibody |
SKU: | CAB2578 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-420 of human FES (NP_001137256.1). |
Sequence: | WQQL QQEL TKTH SQDI EKLK SQYR ALAR DSAQ AKRK YQEA SKDK DRDK AKDK YVRS LWKL FAHH NRYV LGVR AAQL HHQH HHQL LLPG LLRS LQDL HEEM ACIL KEIL QEYL EISS LVQD EVVA IHRE MAAA AARI QPEA EYQG FLRQ YGSA PDVP PCVT FDES LLEE GEPL EPGE LQLN ELTV ESVQ HTLT SVTD ELAV ATEM VFRR QEMV TQLQ QELR NEEE NTHP RERV QLLG KRQV LQEA LQGL QVAL CSQA KLQA QQEL LQTK LEHL GPGE PPPV LLLQ DDRH STSS SEQE REGG R |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FPS; FES |
Positive Sample: | Mouse heart,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Golgi apparatus, Peripheral membrane protein, cytoskeleton, cytosol, focal adhesion. |
Calculated MW: | 93kDa |
Observed MW: | 98kDa |
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 2242 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |