The Ferritin Light Chain Rabbit Monoclonal Antibody is a powerful tool for researchers studying ferritin light chain, a critical protein involved in iron storage and metabolism. This antibody, produced in rabbits, is highly specific and sensitive for detecting Ferritin Light Chain in human samples, making it an ideal choice for Western blotting, immunohistochemistry, and other applications.Ferritin Light Chain plays a crucial role in maintaining iron homeostasis in the body, and dysregulation of its expression has been implicated in various diseases, including iron overload disorders and certain types of cancer.
By using this antibody, researchers can gain valuable insights into the function and regulation of Ferritin Light Chain in healthy and diseased tissues, paving the way for potential therapeutic interventions targeting iron metabolism-related conditions.Overall, the Ferritin Light Chain Rabbit Monoclonal Antibody is a reliable and versatile tool for investigating the role of Ferritin Light Chain in physiological and pathological processes, providing valuable data for researchers in the fields of biochemistry, molecular biology, and medicine.
Product Name:
Ferritin Light Chain Rabbit Monoclonal Antibody
SKU:
CAB11241
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-175 of human Ferritin Light Chain (NP_000137.2).
cytoplasm, cytosol, extracellular exosome, extracellular region
Calculated MW:
20kDa
Observed MW:
18-20kDa
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Purification Method:
Affinity purification
Gene ID:
2512
Clone Number:
ARC57605
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Ferritin Light Chain antibody (CAB11241) at 1:8000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
