Ferritin Heavy Chain Rabbit Monoclonal Antibody (CAB19544)
The Ferritin Heavy Chain Rabbit Monoclonal Antibody (CAB19544) is a valuable tool for researchers studying ferritin, a protein involved in iron storage and regulation in the body. This antibody, produced using rabbit monoclonal technology, is highly specific to the ferritin heavy chain and has been validated for use in various applications, including immunohistochemistry and immunofluorescence.Ferritin is essential for maintaining iron homeostasis in cells and tissues, and dysregulation of ferritin expression has been linked to various diseases, including iron overload disorders and certain types of cancer.
By using this antibody, researchers can accurately detect and analyze ferritin levels in different biological samples, providing insights into the role of ferritin in disease development and progression.Overall, the Ferritin Heavy Chain Rabbit Monoclonal Antibody (CAB19544) offers a reliable and efficient solution for investigating the function of ferritin in biological processes and disease states, making it a valuable asset for studies in the fields of biochemistry, cell biology, and medical research.
Product Name:
Ferritin Heavy Chain Rabbit Monoclonal Antibody
SKU:
CAB19544
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Ferritin Heavy Chain (P02794).
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Purification Method:
Affinity purification
Gene ID:
2495
Clone Number:
ARC0023
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using Ferritin Heavy Chain Rabbit mAb (CAB19544) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
