The FERD3L Polyclonal Antibody (PACO39622) is a valuable tool for researchers studying the FERD3L protein, which is involved in various cellular processes, including cell proliferation, differentiation, and migration. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot experiments.FERD3L, also known as Fer3-like protein, is a potential biomarker for cancer progression and metastasis, as it is overexpressed in various cancer types. By using this antibody, researchers can accurately detect and analyze FERD3L expression in different cell types, aiding in the study of cancer biology and potentially informing the development of targeted therapies.
The FERD3L Polyclonal Antibody (PACO39622) is a reliable tool for investigating the role of FERD3L in cancer development and progression, making it a valuable asset for cancer researchers and clinicians. Enhance your research with this antibody and uncover new insights into the complex mechanisms underlying cancer biology.
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39622 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO39622 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.
Synonyms:
Fer3-like protein (Basic helix-loop-helix protein N-twist) (Class A basic helix-loop-helix protein 31) (bHLHa31) (Nephew of atonal 3) (Neuronal twist), FERD3L, BHLHA31 NATO3 NTWIST
UniProt Protein Function:
FERD3L: Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 7p21.1Cellular Component: nucleusMolecular Function: protein dimerization activity; DNA bindingBiological Process: floor plate development; regulation of neurogenesis; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; cell development
