FECH Rabbit Polyclonal Antibody (CAB8418)
- SKU:
- CAB8418
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | FECH Rabbit Polyclonal Antibody |
SKU: | CAB8418 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_000131.2). |
Sequence: | MRSL GANM AAAL RAAG VLLR DPLA SSSW RVCQ PWRW KSGA AAAA VTTE TAQH AQGA KPQV QPQK RKPK TGIL MLNM GGPE TLGD VHDF LLRL FLDR DLMT LPIQ NKLA PFIA KRRT PKIQ EQYR RIGG GSPI KIWT SKQG EGMV KLLD ELSP NTAP HKYY IGFR YVHP LTEE AIEE MERD GLER AIAF TQYP QYSC STTG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | EPP; FCE; EPP1; FECH |
Positive Sample: | HepG2,HT-29,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 48kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
Purification Method: | Affinity purification |
Gene ID: | 2235 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |