The FDCSP Polyclonal Antibody (PACO3810) is a valuable tool for researchers studying FDCSP, a cell surface protein that has been linked to immune modulation and cancer progression. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the FDCSP protein, this antibody enables researchers to detect and analyze FDCSP expression in various cell types, making it an essential asset for studies in immunology and oncology.FDCSP, also known as follicular dendritic cell secreted protein, is involved in regulating immune responses and has been implicated in promoting tumor growth and metastasis.
Understanding the function of FDCSP is crucial for exploring its potential as a target for cancer therapy and developing strategies to modulate immune responses in the context of cancer and other diseases. The FDCSP Polyclonal Antibody provides a reliable tool for investigating the role of FDCSP in immune regulation and cancer progression, offering researchers valuable insights into potential therapeutic targets and treatment options.
Antibody Name:
FDCSP Antibody
Antibody SKU:
PACO03810
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human FDC-SP.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
FDCSP: Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 4q13|4q13Cellular Component: extracellular region
UniProt Protein Details:
NCBI Summary:
This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion. [provided by RefSeq, Dec 2011]
