The FCRL4 Polyclonal Antibody (CAB10329) is an essential tool for researchers studying FCRL4, a member of the Fc receptor-like family known to play a role in immune regulation and antibody production. This antibody is produced in rabbits and has been rigorously validated for use in Western blot applications, ensuring reliable and accurate results.FCRL4 is a cell surface receptor expressed on B cells and is involved in signaling pathways that regulate immune responses and antibody production. Research on FCRL4 is crucial for understanding its role in autoimmune diseases, B cell signaling, and inflammatory responses.
The FCRL4 Polyclonal Antibody enables the detection and analysis of FCRL4 in various cell types, making it an invaluable tool for studies in immunology and cancer research.By targeting FCRL4, researchers can gain insights into immune system function and develop targeted therapies for diseases characterized by dysregulated immune responses. The FCRL4 Polyclonal Antibody is a valuable resource for scientists looking to explore the role of FCRL4 in health and disease.
Product Name:
FCRL4 Rabbit Polyclonal Antibody
SKU:
CAB10329
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-387 of human FCRL4 (NP_112572.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
57kDa
Observed MW:
57kDa
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.
Purification Method:
Affinity purification
Gene ID:
83417
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCRL4 antibody (CAB10329) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
