The FCRL3 Polyclonal Antibody (CAB10452) is a valuable tool for researchers studying the FCRL3 protein, a member of the Fc receptor-like (FCRL) family that plays a role in immune regulation. This antibody, produced in rabbits, is highly specific for FCRL3 in human samples and has been validated for use in Western blot applications.FCRL3 is known to be involved in regulating immune responses, making it a promising target for research in immunology and cancer biology. By detecting and analyzing FCRL3 protein expression in various cell types, this antibody enables researchers to gain insights into the function of FCRL3 in different disease contexts.
The importance of FCRL3 in immune system modulation highlights its potential as a therapeutic target for conditions such as autoimmune diseases and cancer. By studying the activity of FCRL3 using this antibody, researchers can contribute to the development of novel treatment strategies aimed at manipulating immune responses for therapeutic benefit.
Product Name:
FCRL3 Rabbit Polyclonal Antibody
SKU:
CAB10452
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-180 of human FCRL3 (NP_443171.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
81kDa
Observed MW:
81kDa
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
115352
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCRL3 antibody (CAB10452) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
