FCN3 Rabbit Polyclonal Antibody (CAB17352)
- SKU:
- CAB17352
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | FCN3 Rabbit Polyclonal Antibody |
SKU: | CAB17352 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1). |
Sequence: | LLLG GPAC LKTQ EHPS CPGP RELE ASKV VLLP SCPG APGS PGEK GAPG PQGP PGPP GKMG PKGE PGPR NCRE LLSQ GATL SGWY HLCL PEGR ALPV FCDM DTEG GGWL VFQR RQDG SVDF FRSW SSYR AGFG NQES EFWL GNEN LHQL TLQG NWEL RVEL EDFN GNRT FAHY ATFR LLGE VDHY QLAL GKFS EGTA GDSL SLHS GRPF TTYD ADHD SSNS NCAV IVHG AWWY ASCY RSNL NGRY AVSE AAAH KYGI DWAS GRGV GHPY RRVR MMLR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FCNH; HAKA1; FCN3 |
Positive Sample: | A-549,mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 33kDa |
Observed MW: | 38kDa |
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 8547 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |