The FCN2 Polyclonal Antibody (CAB16690) is a valuable tool for researchers studying FCN2, a protein involved in the immune system's innate response to pathogens. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the FCN2 protein, this antibody enables the detection and analysis of FCN2 in various cell types, making it an ideal choice for studies in immunology and infectious disease research.
FCN2, also known as ficolin-2, plays a crucial role in recognizing and binding to pathogens, leading to their clearance by the immune system. Understanding the function of FCN2 is essential for developing therapies aimed at boosting the innate immune response to infections. Research on FCN2 may also provide insights into its involvement in conditions such as autoimmune diseases and inflammatory disorders, paving the way for novel treatment strategies targeting the immune system.
Product Name:
FCN2 Rabbit Polyclonal Antibody
SKU:
CAB16690
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-290 of human FCN2 (NP_004099.2).
blood microparticle, external side of plasma membrane, extracellular exosome, extracellular region, extracellular space
Calculated MW:
34kDa
Observed MW:
34kDa
The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
2220
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FCN2 Rabbit pAb (CAB16690) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
