The Fcgrt Polyclonal Antibody (CAB8544) is a valuable tool for research involving Fcgrt, a receptor involved in immune regulation and the transportation of IgG across epithelial cells. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the Fcgrt protein, this antibody allows for the detection and analysis of Fcgrt in various cell types, making it an ideal choice for studies in immunology and the understanding of IgG trafficking mechanisms.
Fcgrt, also known as Fc receptor like 1, plays a crucial role in immune function by mediating the transport of IgG across mucosal surfaces, protecting against infections and maintaining immune homeostasis. Its importance in immune response modulation and IgG recycling make it a key target for research related to autoimmunity, infectious diseases, and mucosal immunity. Investigating the function of Fcgrt is essential for developing therapies that target IgG transport and immune response modulation in various disease contexts.
Product Name:
FCGRT Rabbit Polyclonal Antibody
SKU:
CAB8544
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-290 of human FcRn (NP_004098.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
40kDa
Observed MW:
40kDa
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2217
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HL-60 cells, using FCGRT Rabbit pAb (CAB8544) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
