The FCGRt Polyclonal Antibody (PACO39714) is a valuable tool for researchers studying FCGRt, a protein involved in the regulation of immune responses. This antibody, produced using rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding specifically to the FCGRt protein, it enables accurate detection and analysis in various cell types, making it well-suited for investigations in immunology and cancer research.FCGRt, also known as the neonatal Fc receptor, plays a crucial role in immune function by mediating the transport of immunoglobulins across epithelial barriers.
Its involvement in regulating immune responses highlights its relevance in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By studying the function of FCGRt, researchers can gain insights into potential therapeutic targets for modulating immune activity in various disease contexts.
Antibody Name:
FCGRT Antibody (PACO39714)
Antibody SKU:
PACO39714
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Macaca fascicularis
Immunogen:
Recombinant Macaca fascicularis IgG receptor FcRn large subunit p51 protein (24-297AA)
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.
Synonyms:
IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter α chain) (Neonatal Fc receptor), FCGRT, FCRN
UniProt Protein Function:
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system ().