The FCGR3B Polyclonal Antibody (CAB7894) is a versatile tool for research involving FCGR3B, a cell surface receptor that plays a key role in immune responses, particularly in mediating the activation of immune cells. This antibody, produced in rabbits, is highly specific to human samples and has been validated for Western blot applications. By binding to the FCGR3B protein, this antibody allows for precise detection and analysis in a variety of cell types, making it essential for studies in immunology and cancer research.FCGR3B, also known as CD16, is involved in the regulation of antibody-dependent cellular cytotoxicity (ADCC) and plays a crucial role in the immune system's ability to target and destroy infected or abnormal cells.
Its importance in immune response modulation makes it a valuable target for research into diseases such as cancer, autoimmune disorders, and infectious diseases. Understanding the function of FCGR3B is essential for developing targeted therapies that enhance immune responses in these conditions.Overall, the FCGR3B Polyclonal Antibody (CAB7894) is a reliable tool for researchers looking to explore the role of FCGR3B in immune regulation and disease pathology. Its high specificity and sensitivity make it an ideal choice for studies aiming to elucidate the intricate mechanisms of immune response modulation.
Product Name:
FCGR3B Rabbit Polyclonal Antibody
SKU:
CAB7894
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
2215
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCGR3B antibody (CAB7894) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.
