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FCGR3B Rabbit Polyclonal Antibody (CAB7894)

SKU:
CAB7894
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:FCGR3B Rabbit Polyclonal Antibody
SKU:CAB7894
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).
Sequence:MWQL LLPT ALLL LVSA GMRT EDLP KAVV FLEP QWYS VLEK DSVT LKCQ GAYS PEDN STQW FHNE NLIS SQAS SYFI DAAT VNDS GEYR CQTN LSTL SDPV QLEV HIGW LLLQ APRW VFKE EDPI HLRC HSWK NTAL HKVT YLQN GKDR KYFH HNSD FHIP KATL KDSG SYFC RGLV GSKN VSSE TVNI TITQ GLAV STIS SFSP PGYQ VSFC LVMV LLFA VDTG LYFS VKTN I
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:CD16; FCG3; CD16A; CD16b; FCGR3; CD16-I; FCGR3A; FCR-10; FCRIII; FCRIIIb; FCGR3B
Positive Sample:Jurkat,Raji,U-937,THP-1,Mouse liver,Mouse spleen,Mouse thymus,Rat spleen
Conjugate:Unconjugated
Cellular Localization:Cell membrane, GPI-anchor, Lipid-anchor, Secreted.
Calculated MW:26kDa
Observed MW:26kDa/46kDa

The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.

Purification Method:Affinity purification
Gene ID:2215
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using FCGR3B antibody (CAB7894) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 60s.

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