The Fc gamma receptor IIIb (FcγR3b) Polyclonal Antibody (CAB13980) is a valuable tool for researchers working with FcγR3b, a cell surface receptor involved in immune response modulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications.FcγR3b plays a critical role in regulating immune responses by binding to immune complexes and mediating cellular signaling. Its importance in immune function and inflammation makes it a key target for studies in immunology and cancer research.
The FcγR3b Polyclonal Antibody enables accurate detection and analysis of FcγR3b protein expression in various cell types, providing valuable insights into its role in immune regulation and potential therapeutic targets for diseases such as cancer and autoimmune disorders.Overall, the FcγR3b Polyclonal Antibody is an essential tool for researchers aiming to deepen their understanding of immune modulation and inflammatory pathways, paving the way for the development of novel treatments and therapies in the field of immunology.
Product Name:
FCGR3B Rabbit Polyclonal Antibody
SKU:
CAB13980
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FCGR3B (NP_000561.3).
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
2215
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCGR3B antibody (CAB13980) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
