Fcgr3 Antibody (PACO34718)
- SKU:
- PACO34718
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Fcgr3 Antibody (PACO34718)
The FCGR3 Antibody (PAC034718) is a valuable tool for research involving FCGR3, a cell surface receptor known for its role in immune response regulation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the FCGR3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.FCGR3, also known as Fc-gamma receptor III, is a key player in immune regulation, particularly in mediating antibody-dependent cellular cytotoxicity.
Its involvement in immune function makes it a crucial target for research focused on various diseases, including cancer, autoimmune disorders, and inflammatory conditions. Understanding the role of FCGR3 is essential for developing targeted therapies that modulate immune responses in these disease contexts.Overall, the FCGR3 Antibody (PAC034718) offers researchers a reliable tool for studying the function and activity of FCGR3 in different biological processes, ultimately contributing to advancements in disease treatment and immune system modulation.
| Antibody Name: | Fcgr3 Antibody (PACO34718) |
| Antibody SKU: | PACO34718 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Low affinity immunoglobulin γ Fc region receptor III protein (31-215AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. |
| Synonyms: | Low affinity immunoglobulin γ Fc region receptor III (IgG Fc receptor III) (Fc-γ RIII) (FcRIII) (CD antigen CD16), Fcgr3 |
| UniProt Protein Function: | FCGR2A: low affinity receptor for the Fc region of IgGs. Binding to IgG initiates cellular responses against pathogens and soluble antigens. A type I membrane protein found on monocytes, neutrophils and platelets. SHP-1 associates with this protein to modulate signaling events in myeloid cells. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell surface; Receptor, misc. Cellular Component: external side of plasma membrane; integral to membrane; membrane; plasma membrane Molecular Function:IgG binding; IgG receptor activity Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; mast cell activation; neutrophil chemotaxis; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of tumor necrosis factor biosynthetic process; positive regulation of type I hypersensitivity; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; regulation of immune response; serotonin secretion |
| UniProt Code: | P08508 |
| NCBI GenInfo Identifier: | 119877 |
| NCBI Gene ID: | 14131 |
| NCBI Accession: | P08508.1 |
| UniProt Related Accession: | P08508 |
| Molecular Weight: | |
| NCBI Full Name: | Low affinity immunoglobulin gamma Fc region receptor III |
| NCBI Synonym Full Names: | Fc receptor, IgG, low affinity III |
| NCBI Official Symbol: | Fcgr3Â Â |
| NCBI Official Synonym Symbols: | CD16Â Â |
| NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor III |
| UniProt Protein Name: | Low affinity immunoglobulin gamma Fc region receptor III |
| UniProt Synonym Protein Names: | Fc-gamma RIII; FcRIII; CD_antigen: CD16 |
| Protein Family: | CD160 antigen |
| UniProt Gene Name: | Fcgr3Â Â |
| UniProt Entry Name: | FCGR3_MOUSE |
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