The FCGR2B Polyclonal Antibody (PACO02706) is a valuable tool for researchers studying FCGR2B, a cell surface receptor involved in immune regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the FCGR2B protein, this antibody allows for the detection and analysis of FCGR2B in various cell types, making it an ideal choice for studies in immunology and cancer research.FCGR2B, also known as Fc gamma receptor IIB, is a critical player in the modulation of immune responses by inhibiting B cell receptor signaling and regulating antibody production.
Its role in immune regulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and inflammatory conditions. Understanding the function of FCGR2B is essential for the development of therapies aimed at modulating immune responses in these disease contexts.Overall, the FCGR2B Polyclonal Antibody (PACO02706) offers researchers a reliable tool for investigating the function of FCGR2B in immune regulation and disease, providing valuable insights that may lead to the development of novel therapeutic strategies.
Antibody Name:
FCGR2B Antibody
Antibody SKU:
PACO02706
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from human CD32 around the non-phosphorylation site of Y292.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
Low affinity immunoglobulin gamma Fc region receptor II-b
NCBI Summary:
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
