The FCGR2A Polyclonal Antibody (CAB1388) is a valuable tool for researchers studying FCGR2A, a cell surface receptor involved in the regulation of immune responses. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding to the FCGR2A protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in the fields of immunology and cancer research.
FCGR2A, also known as Fc gamma receptor IIA, plays a crucial role in the immune response by mediating the activation of immune cells such as macrophages and neutrophils. Understanding the functions and mechanisms of FCGR2A is critical for investigating diseases such as cancer, autoimmune disorders, and inflammatory conditions. This antibody provides researchers with a reliable tool for exploring the role of FCGR2A in these pathologies and developing novel therapeutic strategies targeting this receptor.
Product Name:
FCGR2A Rabbit Polyclonal Antibody
SKU:
CAB1388
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 34-316 of human FCGR2A (NP_001129691.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
35kDa
Observed MW:
40-50kDa
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
2212
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using FCGR2A antibody (CAB1388) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
